SPIC 抗体
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北京 101111
Quick Overview for SPIC 抗体 (ABIN7862651)
抗原
See all SPIC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SPI-C / Transcription factor Spi-C Antibody
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特异性
- The Ets transcription factor family is comprised of DNA-binding proteins that influence lymphoid development and activity and bind the consensus DNA site GGA(A/T) through a unique winged helix-turn-helix motif known as the Ets domain. Spi-B and Spi-C (also known as SPIC) are closely related Ets family members which share a conserved divergent sequence within the Ets domain that enables their binding to non-canonical AGAA sites. Spi-C is a 248 amino acid protein that localizes to the nucleus and, like other Ets family members, binds DNA as a monomer and plays a role in transcriptional regulation. Addi- tionally, Spi-C is thought to control the development of red pulp macrophages, thereby contributing to iron homeostasis and red blood cell recycling. Human Spi-C shares 65 % amino acid identity with its mouse counterpart, suggesting a conserved role between species.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human SPIC protein
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亚型
- IgG2b
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anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Internal Region) antibody
SPIC 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (AA 1-248) antibodySPIC 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (C-Term) antibodySPIC 适用: 人, 小鼠, Cow, 马, 犬, 豚鼠, 大鼠, 兔, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) antibodySPIC 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) antibodySPIC 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) antibodySPIC 适用: 人, Cow, 马, 犬, 豚鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (C-Term) antibodySPIC 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (AA 148-197) antibodySPIC 适用: 人, 马, 犬, 豚鼠, 大鼠, 兔, 猴, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Middle Region) antibodySPIC 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Internal Region) antibodySPIC 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
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别名
- SPI-C
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背景
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AU019198, C76795, MGC40611, MGC80555, Prf, Pu.1 related factor, Spi C, Spi C transcription factor, Spi-C transcription factor (Spi-1/PU.1 related)
Jurkat or Raji cells.
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分子量
- 29kDa
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基因ID
- 121599, 577097
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UniProt
- Q8N5J4
抗原
-
