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SNW1 抗体

This 小鼠 单克隆 antibody specifically detects SNW1 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7864443
发货至: 中国
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Quick Overview for SNW1 抗体 (ABIN7864443)

抗原

See all SNW1 抗体
SNW1 (SNW Domain Containing 1 (SNW1))

适用

  • 22
  • 15
  • 9
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 19
  • 3
小鼠

克隆类型

  • 19
  • 3
单克隆

标记

  • 22
This SNW1 antibody is un-conjugated

应用范围

  • 16
  • 10
  • 9
  • 5
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  • 3
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

PCRP-SNW1-1C12
  • 原理

    SNW1 Antibody

    特异性

    Nuclear receptor coactivator NCOA62/SNW1 (Nuclear Protein SkiP, SKIIP ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment of human SNW1 protein

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    SNW1 (SNW Domain Containing 1 (SNW1))

    别名

    SNW1

    背景

    Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP

    HeLa or U87 cells. General nuclear expression.

    分子量

    61.49kDa

    基因ID

    22938, 25040

    UniProt

    Q13573

    途径

    Retinoic Acid Receptor Signaling Pathway
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