SNAPC4 抗体
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北京 101111
Quick Overview for SNAPC4 抗体 (ABIN7864515)
抗原
See all SNAPC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SNAPC4 Antibody
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特异性
- TATA-box binding protein (TBP) interactions with TBP-associated factors (TAFs) are required for the transcription of RNA polymerases. One particular TBP-TAF complex, snRNA-activating protein complex (SNAPC), is unusual in that it regulates basal transcription of both RNA polymerase II and III by binding specifically to a non-TATA-box proximal sequence element (PSE). SNAPC consists of five subunits of varying size. SNAPC binds to Oct-1 and TBP, which are activators of snRNA and RNA polymerases, respectively. The POU domain of Oct-1 binds to SNAPC 190 and effectively recruits SNAPC to the PSE. The cooperative binding of SNAPC and Oct-1 to their respective sequence elements is mediated by a nucleosome positioned between the two sequence elements. SNAPC 19 mediates the assembly of the subunits to form a functional SNAPC transcription regulator. SNAPC 50 (also designated PTF≤) contains two zinc finger motifs and binds to SNAPC 43 (also designated PTFé 79oΩ) but not SNAPC 45 (PTFé 79oΩ).
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human SNAPC4 protein
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亚型
- IgG2b, kappa
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anti-Small Nuclear RNA Activating Complex, Polypeptide 4, 190kDa (SNAPC4) (AA 53-162) antibody
SNAPC4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Small Nuclear RNA Activating Complex, Polypeptide 4, 190kDa (SNAPC4) (AA 53-162) antibodySNAPC4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G5 unconjugated
anti-Small Nuclear RNA Activating Complex, Polypeptide 4, 190kDa (SNAPC4) (N-Term) antibodySNAPC4 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Nuclear RNA Activating Complex, Polypeptide 4, 190kDa (SNAPC4) antibodySNAPC4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal SNAAD17A unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- SNAPC4 (Small Nuclear RNA Activating Complex, Polypeptide 4, 190kDa (SNAPC4))
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别名
- SNAPC4
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背景
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FLJ13451, PTFalpha, SNAP190
Human tonsil. HeLa or HDLM-2 cells.
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分子量
- 200kDa
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基因ID
- 6621, 446091
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UniProt
- Q5SXM2
抗原
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