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SIRT3 抗体

This 小鼠 单克隆 antibody specifically detects SIRT3 in WB, ELISA, IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7862849
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIRT3 抗体 (ABIN7862849)

抗原

See all SIRT3 抗体
SIRT3 (Sirtuin 3 (SIRT3))

适用

  • 104
  • 45
  • 23
  • 9
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1

宿主

  • 90
  • 22
  • 2
  • 2
  • 1
小鼠

克隆类型

  • 86
  • 32
单克隆

标记

  • 70
  • 14
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This SIRT3 antibody is un-conjugated

应用范围

  • 104
  • 56
  • 52
  • 14
  • 12
  • 10
  • 9
  • 8
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-SIRT3-1C10
  • 原理

    Sirtuin 3 (SIRT3) Antibody

    特异性

    Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human SIRT3 protein

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    SIRT3 (Sirtuin 3 (SIRT3))

    别名

    Sirtuin 3

    背景

    hSIRT3, Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase, NAD dependent deacetylase sirtuin 3 mitochondrial, Regulatory protein SIR2 homolog 3, SIR2 like protein 3, SIR2-like protein 3, SIR2L3, Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae), Sirtuin type 3, Sirtuin3

    HeLa cells.

    分子量

    43.57kDa

    基因ID

    23410, 716456

    UniProt

    Q9NTG7
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