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Recombinant SELPLG 抗体

This 兔 单克隆 antibody specifically detects SELPLG in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7862069
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant SELPLG 抗体 (ABIN7862069)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This SELPLG antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

PSGL1-8192R
  • 原理

    Recombinant CD162 (Selectin P Ligand) Antibody

    特异性

    CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.Ç 79oΩ

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human SELPLG (CD162) protein

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    CD162

    背景

    CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG

    Human tonsil or spleen.

    分子量

    43-120kDa

    基因ID

    6404, 591014

    UniProt

    Q14242
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