QKI 抗体
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北京 101111
Quick Overview for QKI 抗体 (ABIN7863633)
抗原
See all QKI 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- QKI / Protein Quaking Antibody
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特异性
- QKI, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, QKI functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5'-NACUAAY-N(1,20)-UAAY-3'. Additionally, QKI regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. QKI may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases QKI mRNA-binding affinity. Defects or deletions in the gene encoding QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of QKI exist due to alternative splicing events.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human QKI protein
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亚型
- IgG2c
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anti-Protein Quaking (QKI) antibody
QKI 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Protein Quaking (QKI) antibodyKD Validated QKI 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4595 unconjugated Recombinant Antibody
anti-Protein Quaking (QKI) (AA 1-341) antibody (APC)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 APC
anti-Protein Quaking (QKI) (AA 1-341) antibody (Biotin)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 Biotin
anti-Protein Quaking (QKI) (AA 1-341) antibody (Atto 390)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 Atto 390
anti-Protein Quaking (QKI) (AA 1-341) antibody (Atto 488)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 Atto 488
anti-Protein Quaking (QKI) (AA 1-341) antibody (Atto 594)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 Atto 594
anti-Protein Quaking (QKI) (AA 1-341) antibody (PE)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 PE
anti-Protein Quaking (QKI) (AA 1-341) antibody (PerCP)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 PerCP
anti-Protein Quaking (QKI) (AA 1-341) antibody (FITC)QKI 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S147-6 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- QKI (Protein Quaking (QKI))
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别名
- QKI
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背景
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Homolog of mouse quaking QKI KH domain RNA binding protein, HQK1, Protein quaking, QK1, QK3, QKI, QKI1, Quaking homolog KH domain RNA binding mouse, Quaking isoform 1, Quaking protein, RNA binding protein HQK
HeLa, K562 or MCF7 cells., U87
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分子量
- 37.6kDa
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基因ID
- 9444, 510324
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UniProt
- Q96PU8
抗原
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