LMYC 抗体
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北京 101111
Quick Overview for LMYC 抗体 (ABIN7863177)
抗原
See all LMYC (MYCL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- L-Myc / MYCL1 (Transcription Factor) Antibody
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特异性
- Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human MYCL protein
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亚型
- IgG2b
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anti-Protein L-Myc (MYCL) (AA 186-439) antibody
MYCL 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (AA 135-184) antibodyMYCL 适用: 人, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (AA 257-394) antibodyMYCL 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (AA 80-113), (N-Term) antibodyMYCL 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB47640 unconjugated
anti-Protein L-Myc (MYCL) (AA 271-303) antibodyMYCL 适用: 人 WB 宿主: 兔 Polyclonal RB53775 unconjugated
anti-Protein L-Myc (MYCL) (AA 184-454) antibodyMYCL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (AA 1-206) antibodyMYCL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (AA 1-206) antibodyMYCL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (AA 40-180) antibodyMYCL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein L-Myc (MYCL) (Middle Region) antibodyMYCL 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- LMYC (MYCL) (Protein L-Myc (MYCL))
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别名
- L-Myc
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背景
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bHLHe38, Class E basic helix-loop-helix protein 38, l myc 1 proto-oncogene, Myc related gene from lung cancer, oncogene lmyc, Protein L-Myc-1, v myc avian myelocytomatosis viral oncogene homolog 1 lung carcinoma derived
HeLa cells. Human small cell lung carcinoma.
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分子量
- 40.33kDa
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基因ID
- 4610, 437922
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UniProt
- P12524
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途径
- Warburg Effect
抗原
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