PRMT7 抗体
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北京 101111
Quick Overview for PRMT7 抗体 (ABIN7863260)
抗原
See all PRMT7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PRMT7 Antibody
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特异性
- Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human PRMT7 protein
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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别名
- PRMT7
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背景
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[Myelin basic protein]-arginine N-methyltransferase PRMT7, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7
HeLa, MCF7 or HepG2 cells.
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分子量
- 78.46kDa
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基因ID
- 54496, 640229
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UniProt
- Q9NVM4
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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