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PCGF3 抗体

The 小鼠 单克隆 anti-PCGF3 antibody (Clone PCRP-PCGF3-1D5) (ABIN7861936) specifically detects PCGF3 in IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7861936
发货至: 中国
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Quick Overview for PCGF3 抗体 (ABIN7861936)

抗原

See all PCGF3 抗体
PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

适用

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宿主

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小鼠

克隆类型

  • 9
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单克隆

标记

  • 11
This PCGF3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-PCGF3-1D5
  • 原理

    PCGF3 Antibody

    特异性

    Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human PCGF3 protein

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

    别名

    PCGF3

    背景

    DONG1, PCGF3, PCGF3_HUMAN, Polycomb group ring finger 3, Polycomb group RING finger protein 3, Ring finger protein 3, RING finger protein 3A, RNF3A

    HeLa or MCF-7 cells. Human brain|testis or smooth muscle.

    分子量

    28.12Da

    基因ID

    10336, 731755

    UniProt

    Q3KNV8

    途径

    Chromatin Binding
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