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POGZ 抗体

This 小鼠 单克隆 antibody specifically detects POGZ in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7861934
发货至: 中国
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Quick Overview for POGZ 抗体 (ABIN7861934)

抗原

See all POGZ 抗体
POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

适用

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宿主

  • 24
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小鼠

克隆类型

  • 26
  • 1
单克隆

标记

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This POGZ antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

PCRP-POGZ-1B2
  • 原理

    POGZ Antibody

    特异性

    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human POGZ protein

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

    别名

    POGZ

    背景

    KIAA0461, ZNF280E, ZNF635m, Pogo transposable element with ZNF domain

    HeLa or U87 cells. Human placenta|tonsil or colon.

    分子量

    155.3kDa

    基因ID

    23126, 25040

    UniProt

    Q7Z3K3
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