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PHPT1 抗体

This 小鼠 单克隆 antibody specifically detects PHPT1 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7865402
发货至: 中国
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Quick Overview for PHPT1 抗体 (ABIN7865402)

抗原

See all PHPT1 抗体
PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PHPT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

PHPT1-12053
  • 原理

    PHPT1 Antibody

    特异性

    PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human PHPT1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

    别名

    PHPT1

    背景

    bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14

    Human heart, skeletal muscle or breast.

    分子量

    14kDa

    基因ID

    29085

    UniProt

    Q9NRX4

    途径

    Positive Regulation of Peptide Hormone Secretion
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