NK-1.1/CD161c 抗体
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北京 101111
Quick Overview for NK-1.1/CD161c 抗体 (ABIN7863690)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NK1.1 / CD161c / Klrb1c, Mouse Antibody
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特异性
- NK1.1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene.It is predominantly expressed as a disulfide-linked homodimer on NK cells however, it is also expressed on NK-T cells, a rare population of T lymphocytes.NK1.1 is expressed in some Mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cellsin vitroand rejection of bone marrow allograftsin vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. NK-1.1 is commonly used as a Mouse NK cell marker.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- CD Mouse spleen and bone marrow cells enriched for NK-1+ cells
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亚型
- IgG2a, kappa
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anti-NK-1.1 (AA 101-200) antibody
适用: 小鼠 FACS, WB, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK-1.1 antibody (PerCP-Cy5.5)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PerCP-Cy5.5
anti-NK-1.1 antibody适用: 小鼠 FACS, IP, CyTox 宿主: 小鼠 Monoclonal PK136 unconjugated
anti-NK-1.1 antibody (PE-Cy7)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PE-Cy7
anti-NK-1.1 antibody适用: 小鼠 FACS, IP, IHC, BR, Dep, Act, CMCD 宿主: 小鼠 Monoclonal PK136 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- NK-1.1/CD161c (NK-1.1)
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别名
- NK1.1
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背景
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CD161 antigen-like family member C; CD161c; Killer cell lectin-like receptor subfamily B member 1C (Klrb1c); Klrb1f; Lymphocyte antigen 55c (Ly55c); Lymphocyte antigen 59; Natural killer cell surface protein P1-40; NK1.1; NKR-P1 40; NKR-P1.9; NKR-P1C; NKRP1
MPBMC's or Thymus or Lymph Node.
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分子量
- kDa
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基因ID
- 17059, 480764
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UniProt
- P27814
抗原
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