NPPB 抗体
The 小鼠 单克隆 anti-NPPB antibody is suitable to detect NPPB in samples from 人. It has been validated for IHC.
产品编号 ABIN7863196
发货至:
中国
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Quick Overview for NPPB 抗体 (ABIN7863196)
抗原
See all NPPB 抗体
NPPB
(Natriuretic Peptide Precursor B (NPPB))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This NPPB antibody is un-conjugated
应用范围
Immunohistochemistry (IHC)
克隆位点
NPPB-4493
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原理
- Natriuretic Peptide B / NPPB Antibody
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特异性
- Natriuretic peptides comprise a family of three structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.22. The gene which encodes for CNP maps to human chromosome 2q37.1.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human NPPB (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Natriuretic Peptide Precursor B (NPPB) antibody
NPPB 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- NPPB (Natriuretic Peptide Precursor B (NPPB))
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别名
- Natriuretic Peptide B
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背景
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Brain natriuretic peptide 32, Brain type natriuretic peptide, Gamma brain natriuretic peptide, Natriuretic peptide B, Natriuretic peptide precursor B, natriuretic peptide, brain type, Natriuretic peptides B, natriuretic protein, NPPB
Human heart, liver or uterus.
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分子量
- 25-36kDa (glycosylated BNP precursor), 12kDa (deglycosylated mature BNP)
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基因ID
- 4879
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UniProt
- P16860
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途径
- Hormone Activity
抗原
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