NECAB1 抗体
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Quick Overview for NECAB1 抗体 (ABIN7864146)
抗原
See all NECAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NECAB1 / N-terminal EF-hand calcium binding protein 1 Antibody
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特异性
- Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP1 (N-terminal EF-hand calcium binding protein 1), also known as STIP-1 or neuronal calcium-binding protein 1 (NECAB1), is a 351 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and 2 EF-hand domains. Expressed in brain, EF-CBP1 interacts with copine 6 and Syntaxin, and exists as two alternatively spliced isoforms. The gene encoding EF-CBP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human NECAB1 protein
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))
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别名
- NECAB1
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背景
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EF-hand calcium-binding protein 1, EFCBP1, N-terminal EF-hand calcium-binding protein 1, Neuronal calcium-binding protein 1, STIP-1, synaptotagmin interacting protein 1
Human cerebral cortex, Brain
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分子量
- 41kDa
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基因ID
- 64168, 642655
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UniProt
- Q8N987
抗原
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