MBP 抗体
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北京 101111
Quick Overview for MBP 抗体 (ABIN7863112)
抗原
See all MBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Myelin Basic Protein Antibody
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特异性
- Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. MBP/4271 recognizes an epitope in the 129-138 region of MBP, useful in clinical diagnosis to detect MBP levels.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Reacts with MBP from human, bovine and rat, recognizing epitope 129-138
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亚型
- IgG2a
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anti-Myelin Basic Protein (MBP) antibody
MBP 适用: 人 IHC, ICC, ELISA, FACS 宿主: 小鼠 Monoclonal 2H9 unconjugated
anti-Myelin Basic Protein (MBP) antibodyKD Validated MBP 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1215 unconjugated Recombinant Antibody
anti-Myelin Basic Protein (MBP) (AA 135-190) antibodyMBP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) antibodyMBP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 150-250) antibodyMBP 适用: 人 IHC 宿主: 兔 Monoclonal 390R unconjugated Recombinant Antibody
anti-Myelin Basic Protein (MBP) (AA 220-301) antibodyMBP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 18-222) antibodyMBP 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 182-197) antibodyMBP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 130-136) antibodyMBP 适用: 人, 小鼠, 大鼠, 兔, 绵羊, 山羊, 灵长类 WB, IHC, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-Myelin Basic Protein (MBP) (AA 220-301) antibodyMBP 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C13 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin Basic Protein
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背景
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GDB, Golli MBP, myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MLD, Myelin A1 Protein, basic, Myelin Deficient, Myelin membrane encephalitogenic protein, SHI, Shiverer, SP
Human brain or astrocytoma tissue. Mouse Brain, Rat Brain or Hamster Brain
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分子量
- 14-22kDa
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基因ID
- 4155, 551713
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UniProt
- P02686
抗原
-
