Recombinant MUC16 抗体
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Quick Overview for Recombinant MUC16 抗体 (ABIN7861745)
抗原
See all MUC16 (CA125) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant MUC16 / CA125 (Ovarian Carcinoma Marker) Antibody
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特异性
- CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80 % of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human MUC16 protein
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亚型
- IgG, kappa
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anti-Mucin 16, Cell Surface Associated (CA125) (AA 1-200) antibody
CA125 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C8C8 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 13977-14117) antibodyCA125 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人 IHC 宿主: 兔 Monoclonal OCA125-2349R unconjugated Recombinant Antibody
anti-Mucin 16, Cell Surface Associated (CA125) (AA 2-258) antibodyCA125 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人 IHC 宿主: 小鼠 Monoclonal MUC16-1860 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 14067-14328) antibodyCA125 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (Extracellular Domain) antibodyCA125 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal X325 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 13200 – 13700) antibodyCA125 适用: 人 WB 宿主: 小鼠 Monoclonal 2F1C9 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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别名
- MUC16
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背景
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CA125, Cancer antigen 125, MUC16, Mucin16, Ovarian cancer-related tumor marker CA125
MDA-MB-468 cells. Ovarian Cancer.
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分子量
- >2000kDa
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基因ID
- 94025, 432676
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UniProt
- Q8WXI7
抗原
-
