MED7 抗体
Our Local Distributor
北京 101111
Quick Overview for MED7 抗体 (ABIN7863632)
抗原
See all MED7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- MED7 Antibody
-
特异性
- MED7, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, MED7 functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5'-NACUAAY-N(1,20)-UAAY-3'. Additionally, MED7 regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. MED7 may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases MED7 mRNA-binding affinity. Defects or deletions in the gene encoding MED7 are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of MED7 exist due to alternative splicing events.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant full-length human MED7 protein
-
亚型
- IgG2b
-
-
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibody
MED7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibodyMED7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Mediator Complex Subunit 7 (MED7) (N-Term) antibodyMED7 适用: 人, 小鼠, 犬, 大鼠, 兔, Cow, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 83-111) antibodyMED7 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18104 unconjugated
anti-Mediator Complex Subunit 7 (MED7) (Middle Region) antibodyMED7 适用: 人, 小鼠, 犬, 大鼠, 兔, Cow, 豚鼠, 马, 斑马鱼 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) antibodyMED7 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibodyMED7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 1-233) antibodyMED7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (AA 143-192) antibodyMED7 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 7 (MED7) (N-Term) antibodyMED7 适用: 人, 小鼠, 犬, 大鼠, 兔, Cow, 豚鼠, 马, 斑马鱼, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- MED7 (Mediator Complex Subunit 7 (MED7))
-
别名
- MED7
-
背景
-
Activator recruited cofactor 34 kDa component, ARC34, Cofactor required for Sp1 transcriptional activation, subunit 9, 33 kDa, CRSP complex subunit 9, CRSP9, hMED7, Mediator of RNA polymerase II transcription subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33
HeLa, U-251 MG or CACO-2 cells.
-
分子量
- 27.2kDa
-
基因ID
- 9443, 279902
-
UniProt
- O43513
-
途径
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
-
