MXI1 抗体
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北京 101111
Quick Overview for MXI1 抗体 (ABIN7863173)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MXI1 Antibody
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特异性
- It is now well established that Myc regulation of cell proliferation and differentiation involves a family of related transcription factors. One such factor, Max, is an obligate heterodimeric partner for Myc and can also form heterodimers with at least four related proteins designated Mad 1, Mxi1 (also designated Mad 2), Mad 3 and Mad 4. Like Mad 1 and Mxi1, association of Mad 3 and Mad 4 with Max results in transcriptional repression. Both Myc and the Mad proteins have short half-lives and their synthesis is tightly regulated, while Max expression is constitutive and relatively stable. Two related mammalian cDNAs have been identified and shown to encode Mad- binding proteins. Both possess sequence homology with the yeast transcription repressor Sin3 including four conserved paired amphipathic helix (PAH) domains. mSin3A and mSin3B specifically interact with the Mad proteins via their second paired amphipathic helix domain (PAH2). It has been suggested that Mad-Max heterodimers repress transcription by tethering mSin3 to DNA as corepressors.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human MXI1 protein
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亚型
- IgG2b
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anti-MAX Interactor 1 (MXI1) (AA 1-182) antibody
MXI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-MAX Interactor 1 (MXI1) (Middle Region) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 73-182) antibodyMXI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) antibodyMXI1 适用: 人 DB 宿主: 小鼠 Monoclonal MXI1C2a unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 75-173) antibodyMXI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 176-225) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 170-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 76-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- MXI1 (MAX Interactor 1 (MXI1))
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别名
- MXI1
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背景
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bHLHc11, Class C basic helix-loop-helix protein 11, MAX dimerization protein 2 (MAD2), MAX interacting protein 1, Max interactor 1, Max related transcription factor, MXD2, MXI, MXI1 protein
HeLa or K562 cells.
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分子量
- 26/22/33/21 kDa (isoforms)
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基因ID
- 4601
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UniProt
- P50539
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途径
- Maintenance of Protein Location
抗原
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