Recombinant L1CAM 抗体
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北京 101111
Quick Overview for Recombinant L1CAM 抗体 (ABIN7864805)
抗原
See all L1CAM 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CD171 / NCAM-L1 (L1 Cell Adhesion Molecule) Antibody
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特异性
- L1 (L1 cell adhesion molecule) also known as CAML1, CD171, and HSAS is an adhesion molecule which plays an important role in the nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human L1CAM protein
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亚型
- IgG, kappa
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anti-L1 Cell Adhesion Molecule (L1CAM) antibody
L1CAM 适用: 人, 犬, 猴 WB, FACS, IF 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 猴 WB, FACS 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1143-1257) antibodyL1CAM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 20-197) antibodyL1CAM 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5C6A10 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 653-667), (Extracellular) antibodyL1CAM 适用: 人 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 526-690) antibodyL1CAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 995-1119) antibodyL1CAM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 550-900) antibodyL1CAM 适用: 人 IHC 宿主: 小鼠 Monoclonal 171R unconjugated Recombinant Antibody
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyKD Validated L1CAM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3510 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- CD171
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背景
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CAML1, HSAS1, Hyd, L1 Cell Adhesion Molecule, L1-NCAM, MASA, MIC5, NCAM-L1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, S10, SPG1
Human brain total lysate (WB). PC12 and Neuro-2A (ICC).
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分子量
- full-length isoforms: 140/180/220kDa, proteolytically cleaved form:85 kDa
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基因ID
- 3897, 52818
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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