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Recombinant KRT8 抗体

The 兔 单克隆 anti-KRT8 antibody (Clone KRT8-18-4997R) (ABIN7861615) specifically detects KRT8 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7861615
发货至: 中国
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Quick Overview for Recombinant KRT8 抗体 (ABIN7861615)

抗原

See all KRT8 抗体
KRT8 (Keratin 8 (KRT8))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This KRT8 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

KRT8-18-4997R
  • 原理

    Recombinant Cytokeratin 8/18 Antibody

    特异性

    Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells, there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human CK8 and CK8 proteins

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    KRT8 (Keratin 8 (KRT8))

    别名

    Cytokeratin 8

    背景

    CARD2, CK8, CYK8, CYKER, Cytokeratin Endo A, DreK8, EndoA, K2C8, K8, Keratin 8, Krt 2.8, KRT8, Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18 Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18

    Colon, lung or breast carcinoma., MCF-7 or A431 cells. Human skin

    分子量

    52.5kDa (CK8), 45kDa (CK18)

    UniProt

    P05787
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