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Recombinant KRT6A 抗体

The 兔 单克隆 anti-KRT6A antibody is suitable to detect KRT6A in samples from 人. It has been validated for IHC.
产品编号 ABIN7864236
发货至: 中国
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Quick Overview for Recombinant KRT6A 抗体 (ABIN7864236)

抗原

See all KRT6A 抗体
KRT6A (Keratin 6A (KRT6A))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This KRT6A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

KRT6-8120R
  • 原理

    Recombinant Cytokeratin 6A (KRT6A) (Basal Cell Marker) Antibody

    特异性

    Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment of human KRT6 (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    KRT6A (Keratin 6A (KRT6A))

    别名

    Cytokeratin 6A

    背景

    CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II

    HeLa cells. Human tonsil or basal cell carcinoma (BCC).

    分子量

    56kDa

    基因ID

    3853, 700779

    UniProt

    P02538
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