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Recombinant CDH6 抗体

The 兔 单克隆 anti-CDH6 antibody (Clone CDH6-9300R) (ABIN7863791) specifically detects CDH6 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7863791
发货至: 中国
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Quick Overview for Recombinant CDH6 抗体 (ABIN7863791)

抗原

See all CDH6 抗体
CDH6 (K-Cadherin (CDH6))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CDH6 antibody is un-conjugated

应用范围

  • 78
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Immunohistochemistry (IHC)

克隆位点

CDH6-9300R
  • 原理

    Recombinant Cadherin-6 (CDH6) / K-Cadherin Antibody

    特异性

    This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human Cadherin 6 protein (CDH6) (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    CDH6 (K-Cadherin (CDH6))

    别名

    Cadherin-6

    背景

    Cadherin-6, CDH6, CAD6, KCAD,

    Human kidney or renal cell carcinoma.

    分子量

    130kDa

    基因ID

    1004, 124776

    UniProt

    P55285

    途径

    Cell-Cell Junction Organization
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