Recombinant IL-15 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant IL-15 抗体 (ABIN7863022)
抗原
See all IL-15 (IL15) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant Interleukin-15 (IL-15) Antibody
-
特异性
- Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the æ signaling subunit of the IL-2R. Evidence also suggests that like IL-2, IL-4 and IL-7, IL-15 utilizes the common IL-2RÁ subunit.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant fragment of human IL15 (exact sequence is proprietary)
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- IL-15 (IL15) (Interleukin 15 (IL15))
-
别名
- Interleukin-15
-
背景
-
Interleukin-15 (IL-15), MGC9721
Human placenta, skeletal muscle or adrenal gland.
-
分子量
- 14-15kDa
-
基因ID
- 3600, 654378
-
途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
抗原
-