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IL-15 抗体

The 小鼠 单克隆 anti-IL-15 antibody is suitable to detect IL-15 in samples from 人. It has been validated for IHC.
产品编号 ABIN7863019
发货至: 中国
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Quick Overview for IL-15 抗体 (ABIN7863019)

抗原

See all IL-15 (IL15) 抗体
IL-15 (IL15) (Interleukin 15 (IL15))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-15 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

IL15-4354
  • 原理

    Interleukin-15 (IL-15) Antibody

    特异性

    Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the æ signaling subunit of the IL-2R. Evidence also suggests that like IL-2, IL-4 and IL-7, IL-15 utilizes the common IL-2RÁ subunit.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment of human IL15 (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    IL-15 (IL15) (Interleukin 15 (IL15))

    别名

    Interleukin-15

    背景

    Interleukin-15 (IL-15), MGC9721

    Human placenta, skeletal muscle or adrenal gland.

    分子量

    14-15kDa

    基因ID

    3600, 654378

    途径

    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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