IGF2BP2 抗体
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北京 101111
Quick Overview for IGF2BP2 抗体 (ABIN7861504)
抗原
See all IGF2BP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IGF2BP2 Antibody
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特异性
- IGF2BP2 (Insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type two diabetes mellitus.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human IGF2BP2 protein
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亚型
- IgG2, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))
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别名
- IGF2BP2
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背景
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Hepatocellular carcinoma autoantigen p62, IGF 2 mRNA binding protein 2, IGF II mRNA binding protein 2, IMP2, Insulin like growth factor 2 mRNA binding protein 2, p62, VICKZ 2, VICKZ family member 2, VICKZ2
HeLa cells.
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分子量
- 105kDa
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基因ID
- 10644, 35354
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UniProt
- Q9Y6M1
抗原
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