Recombinant GSTM3 抗体
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Quick Overview for Recombinant GSTM3 抗体 (ABIN7865038)
抗原
See all GSTM3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Glutathione S-Transferase Mu3 (GSTM3) Antibody
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特异性
- Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely ±, é 79oΩ, é 79oΩ, é 79oΩ, 79oΩ, è 79oΩ, è 79oΩ and è 79oΩ, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM3 protein is selectively expressed in the testis and brain. GSTM3 may also be tumor suppressive in RCC, as low expression has been demonstrated to correlate with RCC risk and poor prognosis in post-op patients.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human GSTM3 protein
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亚型
- IgG2b, kappa
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anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 93-206) antibody
GSTM3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 1-225) antibodyGSTM3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) antibodyGSTM3 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CPTC-GSTMu3-1 unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) (C-Term) antibodyGSTM3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 101-225) antibodyGSTM3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 8-223) antibodyGSTM3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) antibodyGSTM3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) antibodyGSTM3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 1-225) antibodyGSTM3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) antibodyGSTM3 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))
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别名
- Glutathione S-Transferase Mu3
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背景
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brain GST antibody, brain type mu glutathione S transferase, GST class mu 3, GST5, GSTB, GSTM3-3, S (hydroxyalkyl)glutathione lyase M3, glutathione S transferase M3 (brain)
Brain|T-47D, HeLa cell lysate. Human liver|testis or kidney.
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分子量
- 26kDa
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基因ID
- 2947, 2006
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UniProt
- P21266
抗原
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