GCLM 抗体
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北京 101111
Quick Overview for GCLM 抗体 (ABIN7861364)
抗原
See all GCLM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GCLM (DNA Mismatch Repair Protein) Antibody
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特异性
- G-glutamylcysteine synthetase (g-GCS) is the rate limiting enzyme for glutathione (L-g-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. g-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. The human g-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human g-GCS gene encoding the regulatory subunit maps to chromosome 1p22.1. The two subunits of g-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human GCLM protein
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亚型
- IgG2a, kappa
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anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 246-274), (C-Term) antibody
GCLM 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22980 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 40-251) antibodyGCLM 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274), (Regulatory Subunit) antibodyGCLM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) antibodyKD Validated GCLM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5535 unconjugated Recombinant Antibody
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 245-274), (C-Term) antibodyGCLM 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (N-Term) antibodyGCLM 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 182-231) antibodyGCLM 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴, 犬, 豚鼠, 马, 斑马鱼, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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别名
- GCLM
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背景
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Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, GCLM, GCS light chain, GLCLR, Glutamate--cysteine ligase modifier subunit, Glutamate--cysteine ligase regulatory subunit, GSC light chain
Human colon carcinoma (IHC).
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分子量
- 31kDa
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基因ID
- 2730, 315562
抗原
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