GCM2 抗体
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北京 101111
Quick Overview for GCM2 抗体 (ABIN7864587)
抗原
See all GCM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GCM2 Antibody
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特异性
- Glial cells missing homolog 2 (GCM2), also known as Chorion-specific tran2scription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a tran2scription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal reces2sive condition characterized by hypocalcemia and hyperphosphatemia.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human GCM2 protein
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
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别名
- GCM2
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背景
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hGCMb | GCMB
HeLa or MCF-7 cells.
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分子量
- 56.61kDa
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基因ID
- 9247, 478588
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UniProt
- O75603
抗原
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