GTF2A1 抗体
Our Local Distributor
北京 101111
Quick Overview for GTF2A1 抗体 (ABIN7862925)
抗原
See all GTF2A1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- GTF2A1/ TFIIA (Transcription Factor) Antibody
-
特异性
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in formation of the preinitiation complex (PIC) which contains several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-°™, TFIIA- æ and TFIIA-Á, all of which associate with both TBP and TAF (TBP-associated factor). TFIIA functions to stabilize the interaction between TFIID and DNA by binding directly to TBP and the DNA (at the TATA box), thus forming a TBP/TFIIA/TATA complex which mediates the transcriptional output of a gene.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant full-length human GTF2A1 protein
-
亚型
- IgG2b
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- GTF2A1 (General Transcription Factor IIA, 1, 19/37kDa (GTF2A1))
-
别名
- GTF2A1
-
背景
-
General transcription factor IIA 1 19/37 kDa, General transcription factor IIA subunit 1, Glucose regulated protein 58kD pseudogene, TFIIA alpha p55, isoform 1, TFIIA p19 subunit, TFIIA p35 subunit, TFIIAL, Transcription initiation factor IIA beta chain, Transcription initiation factor IIA subunit 1, Transcription initiation factor TFIIA 42 kDa subunit
HeLa or MCF-7 cells.
-
分子量
- 41.51kDa
-
基因ID
- 2957, 592334
-
UniProt
- P52655
抗原
-