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EpCAM 抗体

This 小鼠 单克隆 antibody specifically detects EpCAM in FACS 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7861277
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EpCAM 抗体 (ABIN7861277)

抗原

See all EpCAM (EPCAM) 抗体
EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This EpCAM antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC)

克隆位点

Ber-EP4
  • 原理

    Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) Antibody

    特异性

    Recognizes a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. It has been reported that this epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Human breast cancer MCF-7 cells

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

    别名

    Ep-CAM

    背景

    Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, EGP40, Epithelial Cell Adhesion Molecule, Epithelial Glycoprotein 314, ESA, KSA, TACD1, TACSTD1, TROP1, Tumor-associated Calcium Signal Transducer 1

    MCF-7 or HT29 cells. Breast tumor.

    分子量

    40-43kDa

    基因ID

    4072, 542050

    UniProt

    P16422
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