Recombinant EGFRviii 抗体
This 兔 单克隆 antibody specifically detects EGFRviii in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7862726
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant EGFRviii 抗体 (ABIN7862726)
抗原
EGFRviii (EGFRv3)
(EGFR vIII (EGFRv3))
抗体类型
Recombinant Antibody
适用
人
宿主
兔
克隆类型
单克隆
标记
This EGFRviii antibody is un-conjugated
应用范围
Immunohistochemistry (IHC)
克隆位点
GFR-2600R
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原理
- Recombinant EGFRvIII (Epidermal Growth Factor Receptor, Variant III) Antibody
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特异性
- EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)
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亚型
- IgG, kappa
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anti-EGFR vIII (EGFRv3) (AA 1-50) antibody
EGFRv3 适用: 人 FACS, WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
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别名
- EGFRvIII
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背景
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Erbb1 variant III, ERBB1 variant III, HER1 variant III, Proto-oncogene c-ErbB-1 variant III, Receptor Tyrosine Protein Kinase variant III, ErbB1 variant III
A431 cells. Placenta, Breast, Colon or Bladder Carcinoma
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分子量
- ~145kDa (vIII variant)
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基因ID
- 1956, 488293
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UniProt
- P00533
抗原
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