Recombinant CD39 抗体
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北京 101111
Quick Overview for Recombinant CD39 抗体 (ABIN7863892)
抗原
See all CD39 (ENTPD1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CD39 / ENTPD1 (Marker of Tumor-specific T cells) Antibody
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特异性
- CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP, and ultimately generating Adenosine. Intracellular CD39 undergoes glycosylation at six N-glycosylation sites and translocates to the membrane in order to be an active enzyme. Alternative splicing gives rise to three CD39 isoforms, vascular, placenta I and placenta II. The placenta I isoform differs at the amino terminus whereas the placenta II isoform is missing amino acids 300-510 at the C-terminus. CD39 is expressed in vascular tissues including placenta, lung, skeletal muscle and kidney, as well as endothelium, smooth muscle, cardiac cells, lymphocytes, such as activated B cells, activated NK cells, macrophages, Dendridic cells and platelets. CD39 may be used as an anti-thrombic agent for pre-treating patients at risk for coronary artery occlusion and thrombic stroke.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human CD39 protein
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亚型
- IgG, kappa
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anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-180) antibody
ENTPD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 300-350) antibodyENTPD1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Monoclonal BLR285L unconjugated Recombinant Antibody
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-179) antibodyENTPD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8E9F2 unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-179) antibodyENTPD1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 6H12F9 unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibodyENTPD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 241-486) antibodyENTPD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 316-474) antibodyENTPD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 398-411), (Extracellular) antibodyENTPD1 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibodyENTPD1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibody (FITC)ENTPD1 适用: 人 FACS 宿主: 小鼠 Monoclonal TU66 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
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别名
- CD39
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背景
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ATPDase, DKFZp686D194, DKFZp686I093, Ecto apyrase, Ecto ATP diphosphohydrolase, Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, FLJ40921, FLJ40959, Lymphoid cell activation antigen, NTPDase 1, SPG64
Human tonsil or lymph node.
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分子量
- 70-100 kDa
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基因ID
- 953, 576612
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UniProt
- P49961
抗原
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