AKR1C1 抗体
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Quick Overview for AKR1C1 抗体 (ABIN7861224)
抗原
See all AKR1C1 (DDH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Aldo-keto Reductase Family 1 Member C1 / DD1 Antibody
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特异性
- DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human full-length AKR1C1 protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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别名
- Aldo-keto Reductase Family 1 Member C1
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背景
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2-dihydrobenzene-1, 2-diol dehydrogenase, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, C9, Chlordecone reductase homolog HAKRC, DD1/DD2, DDH1, Dihydrodiol dehydrogenase 1/2, H37, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase, Type II 3 alpha hydroxysteroid dehydrogenase
Human liver or stomach tissue.
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分子量
- 37kDa
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基因ID
- 1645, 460260
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UniProt
- Q04828
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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