Recombinant D-Dimer 抗体
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Quick Overview for Recombinant D-Dimer 抗体 (ABIN7865248)
抗原
See all D-Dimer 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant D-Dimer / Fibrinogen gamma chain Antibody
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特异性
- The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities and are mitogens for several cell types. This antibody is directed against a neoantigenic determinant expressed on the human fragment D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human FGA protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-D-Dimer antibody
适用: 人 ELISA, AGG, LA 宿主: 兔 Chimeric 3B6 unconjugated Recombinant Antibody
anti-D-Dimer antibody适用: 人 ELISA, WB, PrA 宿主: 小鼠 Monoclonal DD1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- D-Dimer
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背景
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fibrinogen, gamma polypeptide testicular tissue protein Li 70
HepG2 or A-549 cells. Human kidney.
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分子量
- 57kDa
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基因ID
- 2266
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UniProt
- P02679
抗原
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