CRYAB 抗体
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北京 101111
Quick Overview for CRYAB 抗体 (ABIN7861153)
抗原
See all CRYAB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Crystallin Alpha B Antibody
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特异性
- Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into ±, ≤ and ≥ families, and the ≤- and ≥-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. ±-crystallins consist of three gene products, ±A-, ±B- and ±C-crystallin, which are members of the small heat shock protein family (HSP 20). ±-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, ±-crystallins do not renature these proteins. Expression of ±A-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human ±B-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of ±B-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human full-length CRYAB protein
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亚型
- IgG2, kappa
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anti-Crystallin, alpha B (CRYAB) (AA 1-175) antibody
CRYAB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha B (CRYAB) antibodyCRYAB 适用: 人 WB, IHC, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 6G5 unconjugated
anti-Crystallin, alpha B (CRYAB) antibodyCRYAB 适用: 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal CPTC-CRYAB-1 unconjugated
anti-Crystallin, alpha B (CRYAB) (AA 30-151) antibodyCRYAB 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha B (CRYAB) antibody (Atto 488)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Atto 488
anti-Crystallin, alpha B (CRYAB) antibody (Atto 594)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Atto 594
anti-Crystallin, alpha B (CRYAB) antibody (PE)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 PE
anti-Crystallin, alpha B (CRYAB) antibody (PerCP)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 PerCP
anti-Crystallin, alpha B (CRYAB) antibody (Biotin)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Biotin
anti-Crystallin, alpha B (CRYAB) antibody (FITC)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- Crystallin Alpha B
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背景
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AACRYA, Alpha B crystallin, Alpha-crystallin B chain, CRYA2, CTTP2, Heat shock 20 kD like protein, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY REN 27, Rosenthal fiber component
Huma heart|kidney or brain.
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分子量
- Predicted: 20kDa, Observed: 22-30kDa
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基因ID
- 1410, 53454
抗原
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