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CKM 抗体

The 小鼠 单克隆 anti-CKM antibody (Clone CKMM-3341) (ABIN7862630) specifically detects CKM in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7862630
发货至: 中国
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Quick Overview for CKM 抗体 (ABIN7862630)

抗原

See all CKM 抗体
CKM (Creatine Kinase, Muscle (CKM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CKM antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

CKMM-3341
  • 原理

    Creatine Kinase MM Antibody

    特异性

    T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length CKM protein

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CKM (Creatine Kinase, Muscle (CKM))

    别名

    Creatine Kinase MM

    背景

    CKM, CKMM, Creatine kinase M, Creatine kinase M chain, Creatine kinase M type, Creatine kinase M-type, Creatine kinase muscle, Creatine kinase, muscle type, M-CK, MCK, Muscle creatine kinase

    Human heart tissue. Skeletal muscle lysate.

    分子量

    43kDa

    基因ID

    1158, 334347

    UniProt

    P06732
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