CEBPE 抗体
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北京 101111
Quick Overview for CEBPE 抗体 (ABIN7861006)
抗原
See all CEBPE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CEBPE Antibody
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特异性
- The transcription factor C/EBP ± (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP ± regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP ± uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic ± helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP ± appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP ≤, C/EBP ≥, C/EBP t and C/EBP μ, all of which exhibit similar DNA-binding specificities and affinities to C/EBP ±. Furthermore, C/EBP ≤ and C/EBP t readily form heterodimers both with each other as well as with C/EBP ±.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human CEBPE protein
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
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别名
- CEBPE
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背景
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C/EBP epsilon, CCAAT/enhancer binding protein (C/EBP) epsilon, CCAAT/enhancer binding protein epsilon, CCAAT/enhancer-binding protein epsilon, CEBPE, CRP1
HeLa or MCF-7 cells.
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分子量
- 32/30/27/14kDa
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基因ID
- 1053, 558308
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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