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CA8 抗体

The 小鼠 单克隆 anti-CA8 antibody (Clone CA8-6572) (ABIN7863512) specifically detects CA8 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7863512
发货至: 中国
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Quick Overview for CA8 抗体 (ABIN7863512)

抗原

See all CA8 抗体
CA8 (Carbonic Anhydrase VIII (CA8))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CA8 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

CA8-6572
  • 原理

    Carbonic Anhydrase VIII Antibody

    特异性

    The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human CA8 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CA8 (Carbonic Anhydrase VIII (CA8))

    别名

    Carbonic Anhydrase VIII

    背景

    CA-VIII, CALS, CARP, MGC120502, MGC99509

    Human cerebellum. Selective expression in Purkinje cells. HEK-293 or K-562 cell lines.

    分子量

    32.97kDa

    基因ID

    767, 654388

    UniProt

    P35219
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