Annexin A2 抗体
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北京 101111
Quick Overview for Annexin A2 抗体 (ABIN7860904)
抗原
See all Annexin A2 (ANXA2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Annexin A2 Antibody
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特异性
- The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human Annexin A2 protein
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Annexin A2 (ANXA2)
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别名
- Annexin A2
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背景
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Annexin A2, Annexin II, heavy chain, ANX2, ANX2L4, arylsulfatase B, CAL1H, calpactin I heavy polypeptide (p36), Calpactin I heavy polypeptide, chromobindin 8, Epididymis secretory protein Li 270, HEL S 270, LIP2, Lipocortin II, LPC2, LPC2D, P36 protein, PAP-IV, Placental anticoagulant protein IV, Protein I
HeLa or A549 cells. Human colon cancer.
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分子量
- 36kDa
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基因ID
- 302, 511605
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途径
- S100 Proteins
抗原
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