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Annexin A2 抗体

The 小鼠 单克隆 anti-Annexin A2 antibody is suitable to detect Annexin A2 in samples from 人. It has been validated for IHC.
产品编号 ABIN7864756
发货至: 中国
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Quick Overview for Annexin A2 抗体 (ABIN7864756)

抗原

See all Annexin A2 (ANXA2) 抗体
Annexin A2 (ANXA2)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Annexin A2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

3D5-4
  • 原理

    Annexin A2 Antibody

    特异性

    The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human Annexin A2 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Annexin A2 (ANXA2)

    别名

    Annexin A2

    背景

    Annexin A2, Annexin II, heavy chain, ANX2, ANX2L4, arylsulfatase B, CAL1H, calpactin I heavy polypeptide (p36), Calpactin I heavy polypeptide, chromobindin 8, Epididymis secretory protein Li 270, HEL S 270, LIP2, Lipocortin II, LPC2, LPC2D, P36 protein, PAP-IV, Placental anticoagulant protein IV, Protein I

    HeLa or A549 cells. Human colon cancer.

    分子量

    36kDa

    基因ID

    302, 511605

    途径

    S100 Proteins
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