Recombinant Annexin a1 抗体
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Quick Overview for Recombinant Annexin a1 抗体 (ABIN7864755)
抗原
See all Annexin a1 (ANXA1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Annexin A1 / (Hairy Cell Leukemia Marker) Antibody
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特异性
- The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human Annexin A1 protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin A1
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背景
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ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35
HeLa or A549 cells. Human esophagus, placenta or prostate.
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分子量
- 38kDa
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基因ID
- 301, 494173
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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