ALDH1L1 抗体
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北京 101111
Quick Overview for ALDH1L1 抗体 (ABIN7860870)
抗原
See all ALDH1L1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ALDH1L1 Antibody
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特异性
- Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1L1 (aldehyde dehydrogenase 1 family member L1), also known as FTHFD or 10-FTHFD (10-formyltetrahydrofolate dehydrogenase), is a cytosolic protein that is developmentally regulated in the cerebellum. ALDH1L1 binds to folate and catalyzes the conversion of 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF). This suggests a possible role for ALDH1L1 in the regulation of cellular THF levels as well as in the inhibition of cell proliferation (as 10-FTHF is essential for the synthesis of purine). In addition, the overexpression of ALDH1L1 can restrict cell proliferation in vitro.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human ALDH1L1 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibody
ALDH1L1 适用: 人, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibodyALDH1L1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) (AA 803-902) antibodyALDH1L1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) (AA 282-424) antibodyALDH1L1 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, IF, ELISA, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) (AA 803-902) antibodyALDH1L1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) (AA 402-902) antibodyALDH1L1 适用: 人, 大鼠 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibodyALDH1L1 适用: 人, 大鼠 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibodyMicroarray verified ALDH1L1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB973566 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibodyMicroarray verified ALDH1L1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB245806 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) antibodyALDH1L1 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI5G8 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))
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别名
- ALDH1L1
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背景
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10-FTHFDH, Aldehyde dehydrogenase family 1 member L1, aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, DKFZp781N0997, EC 1.5.1.6, FDH, formyltetrahydrofolate dehydrogenase, FTHFD
Human kidney or liver.
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分子量
- 99kDa
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基因ID
- 10840, 434435
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UniProt
- O75891
抗原
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