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Recombinant Parvin, beta 抗体 (N-Term)

The 兔 单克隆 anti-Parvin, beta antibody is suitable to detect Parvin, beta in samples from 人. It has been validated for IHC.
产品编号 ABIN7860822
发货至: 中国
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Quick Overview for Recombinant Parvin, beta 抗体 (N-Term) (ABIN7860822)

抗原

See all Parvin, beta (PARVB) 抗体
Parvin, beta (PARVB)

抗体类型

Recombinant Antibody

适用

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宿主

  • 14
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克隆类型

  • 13
  • 7
单克隆

标记

  • 20
This Parvin, beta antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

PARVB-8214R
  • 抗原表位

    • 4
    • 3
    • 1
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    AA 1-91, N-Term

    原理

    Recombinant Beta-Parvin Antibody

    特异性

    Beta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007).

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    N-terminal region (residues 1-91) of human b-parvin

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Parvin, beta (PARVB)

    别名

    Beta-Parvin

    背景

    Affixin, beta-parvin, CGI-56, Parvb

    HeLa cell lysate. HeLa cells. Human stomach.

    分子量

    41kDa

    基因ID

    29780, 475074

    UniProt

    Q9HBI1
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