Recombinant Filaggrin 抗体 (N-Term)
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Quick Overview for Recombinant Filaggrin 抗体 (N-Term) (ABIN7865487)
抗原
See all Filaggrin (FLG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Recombinant Filaggrin (Keratinocyte Differentiation Marker) Antibody
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特异性
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Prokaryotic recombinant protein corresponding to a portion of the N-terminus of the human filaggrin molecule
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亚型
- IgG1, kappa
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anti-Filaggrin (FLG) (AA 119-336) antibody
FLG 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC 宿主: 小鼠 Monoclonal FLG-1561 unconjugated
anti-Filaggrin (FLG) (AA 998-1104) antibodyFLG 适用: 人 IHC 宿主: 小鼠 Monoclonal FLG-1563 unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC 宿主: 兔 Monoclonal FLG-1957R unconjugated Recombinant Antibody
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC 宿主: 小鼠 Monoclonal rFLG-1561 unconjugated Recombinant Antibody
anti-Filaggrin (FLG) (AA 3838-4061) antibodyFLG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) antibodyFLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 1-261) antibodyFLG 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 3905-4031) antibodyFLG 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (Ser376) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Filaggrin (FLG)
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别名
- Filaggrin
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背景
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ATOD2, Epidermal Filaggrin, Filaggrin, Filaggrin precursor, Fillagrin, FLG, Profilaggrin
Human skin.
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分子量
- 26-45kDa (Processed), 350kDa (Profilaggrin)
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基因ID
- 2312, 654510
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UniProt
- P20930
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途径
- Sensory Perception of Sound, Stem Cell Maintenance
抗原
-
