PLP 抗体 (C-Term)
The 小鼠 单克隆 anti-PLP antibody (Clone PLP1-4259) (ABIN7863245) specifically detects PLP in IHC.
The antibody is reactive with Cow, Gallotia galloti, 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7863245
发货至:
中国
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中国
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Quick Overview for PLP 抗体 (C-Term) (ABIN7863245)
抗原
PLP
(Proteolipid Protein (PLP))
适用
Cow, Gallotia galloti, 人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
应用范围
Immunohistochemistry (IHC)
克隆位点
PLP1-4259
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抗原表位
- AA 272-277, C-Term
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原理
- Proteolipid Protein / Myelin PLP Antibody
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特异性
- Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PLP (Proteolipid Protein (PLP))
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别名
- Proteolipid Protein
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背景
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Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20
Human brain tissue.
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分子量
- 23-25kDa
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基因ID
- 5354, 1787
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UniProt
- P60201
抗原
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