Paired Box 3 抗体 (C-Term)
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Quick Overview for Paired Box 3 抗体 (C-Term) (ABIN7864043)
抗原
See all Paired Box 3 (PAX3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- PAX3 Antibody
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特异性
- Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Synthetic peptide (quail) from the C-terminus
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Paired Box 3 (PAX3)
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别名
- PAX3
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背景
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CDHS, HUP2, Paired box 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired domain gene HuP2, PAX3/FKHR fusion gene, Sp, splotch, Waardenburg syndrome 1, WS1, WS3
Human skin and skeletal muscle tissue.
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分子量
- 56kDa
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基因ID
- 5077, 42146
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UniProt
- P23760
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途径
- Sensory Perception of Sound, Tube Formation
抗原
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