Recombinant MUM1 抗体 (C-Term)
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Quick Overview for Recombinant MUM1 抗体 (C-Term) (ABIN7860709)
抗原
See all MUM1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Recombinant MUM1 / IRF4 (Transcription Factor) Antibody
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特异性
- MUM1 is one of nuclear transcription factors necessary for development and activation of B lymphocytes. MUM1 belongs to the IRF gene family containing at least 10 widely expressed genes with similar DNA binding motif all involved in regulation of cell growth, transformation and induction of apoptosis as well as development of T-cell immune response. The synonym of MUM1 is Interferon Regulatory Factor 4 (IRF4). MUM1 is found mainly in B-cell lymphoma and melanocytic lesions. Significant variation in positivity mainly due to chromosomal translocations involving MUM1 gene among T-cell lymphomas is observed. MUM1 is useful in a panel with other markers for subclassification of malignant lymphomas and identification of plasma cell differentiation. Particularly MUM1 may be useful for the identification of plasma cell differentiation when morphologic evidence is lacking and Ig light chains are difficult to interpret.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (corresponding to C-terminal) of IRF4 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Melanoma Associated Antigen (Mutated) 1 (MUM1) antibody
MUM1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Melanoma Associated Antigen (Mutated) 1 (MUM1) (AA 401-500) antibodyMUM1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Antigen (Mutated) 1 (MUM1) (AA 1-711) antibodyMUM1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Associated Antigen (Mutated) 1 (MUM1) antibodyMUM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Antigen (Mutated) 1 (MUM1) (AA 671-699), (C-Term) antibodyMUM1 适用: 人 WB 宿主: 兔 Polyclonal RB37724 unconjugated
anti-Melanoma Associated Antigen (Mutated) 1 (MUM1) (AA 671-699) antibodyMUM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.
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有效期
- 24 months
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- MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))
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别名
- MUM1
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背景
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Interferon regulatory factor 4, IRF 4, LSIRF, Lymphocyte specific interferon regulatory factor, Multiple myeloma oncogene 1, MUM1, NFEM5, PU.1 interaction partner, Sfpi1/PU.1 interaction partner, Transcriptional activator PIP
Human tonsil or diffuse large B-cell lymphoma (DLBCL).
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分子量
- 52kDa
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基因ID
- 3662, 401013
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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