Cadherin pan 抗体 (C-Term)
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Quick Overview for Cadherin pan 抗体 (C-Term) (ABIN7860686)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Pan-Cadherin Antibody
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特异性
- Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as ≤-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin 6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human C-terminal of Pan-Cadherin (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Cadherin pan (Cadherin Pan)
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别名
- Pan-Cadherin
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背景
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Cadherin, CDH3, CDHP, 7B4 antigen, Cadherin-1, Cadherin-2, Cadherin-3, Cadherin-4, Cadherin-5, CAM 120/80, CD144, CD324, CD325, Cdh4, CDH5, CDHE, CDHN, E-cadherin, Epithelial cadherin, N-cadherin, NCAD, Neural cadherin, P-cadherin, Placental cadherin, UVO, Uvomorulin, Vascular endothelial cadherin
colon|Human heart|prostate or brain.
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分子量
- 120 kDa
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基因ID
- 999, 1000, 1001
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UniProt
- P12830, P19022, P22223, P33151, P55283
抗原
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