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Liver Arginase 抗体 (Arg1)

The 小鼠 单克隆 anti-Liver Arginase antibody is suitable to detect Liver Arginase in samples from 人, 大鼠, 小鼠, 豚鼠 和 Hamster. It has been validated for WB 和 IHC.
产品编号 ABIN7860678
发货至: 中国
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Quick Overview for Liver Arginase 抗体 (Arg1) (ABIN7860678)

抗原

See all Liver Arginase (ARG1) 抗体
Liver Arginase (ARG1) (Arginase, Liver (ARG1))

适用

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人, 大鼠, 小鼠, 豚鼠, Hamster

宿主

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小鼠

克隆类型

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单克隆

标记

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This Liver Arginase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

ARG1-9448
  • 抗原表位

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    AA 11-97, Arg1

    原理

    Arginase 1 (Hepatocellular Carcinoma Marker) Antibody

    特异性

    Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Liver Arginase (ARG1) (Arginase, Liver (ARG1))

    别名

    Arginase 1

    背景

    Arginase 1, ARG1, liver-type arginase, type I arginase

    Human Liver, Mouse Liver, Rat Liver, Hamster Liver or Guinea pig Liver

    分子量

    35-38kDa

    基因ID

    383, 440934

    UniProt

    P05089

    途径

    Cellular Response to Molecule of Bacterial Origin
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