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Neuropilin 1 抗体 (AA 700-900)

The 小鼠 单克隆 anti-Neuropilin 1 antibody is suitable to detect Neuropilin 1 in samples from 人. It has been validated for IHC.
产品编号 ABIN7860594
发货至: 中国
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Quick Overview for Neuropilin 1 抗体 (AA 700-900) (ABIN7860594)

抗原

See all Neuropilin 1 (NRP1) 抗体
Neuropilin 1 (NRP1)

适用

  • 144
  • 72
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 116
  • 33
  • 13
  • 8
  • 4
小鼠

克隆类型

  • 96
  • 78
单克隆

标记

  • 81
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  • 16
  • 7
  • 7
  • 4
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This Neuropilin 1 antibody is un-conjugated

应用范围

  • 113
  • 55
  • 45
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  • 22
  • 15
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  • 4
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  • 1
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Immunohistochemistry (IHC)

克隆位点

NRP1-4620
  • 抗原表位

    • 15
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-900

    原理

    NRP1 / Neuropilin-1 Antibody

    特异性

    Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa700-900) of human NRP1 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Neuropilin 1 (NRP1)

    别名

    NRP1

    背景

    A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD304, Neuropilin-1, Neuropilin1, NP1, NPN1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R

    Human placenta|kidney or lymph node.|testis

    分子量

    130kDa

    基因ID

    8829, 131704

    UniProt

    O14786

    途径

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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